WebT-2 toxin is the most toxic type A trichothecene mycotoxin. It is the secondary metabolite of the Fusarium fungi, and is common in grain and animal feed. Toxic effects have been … T-2 Mycotoxin (pronounced as 'Tee-Two') is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and animals. The clinical condition it causes is alimentary toxic aleukia and a host of symptoms related to organs as diverse as the skin, airway, and … See more Alimentary toxic aleukia (ATA), a disease which is caused by trichothecenes like T-2 mycotoxin, killed many thousands of USSR citizens in the Orenburg District in the 1940s. It was reported that the mortality rate was 10% of the … See more T-2 mycotoxin is produced naturally by Fusarium fungi of which the most important species are: F. sporotrichioides, F. langsethiae, F. … See more ADME Properties Absorption & Exposure Humans and animals are generally exposed to T-2 mycotoxins through food. Certain grains can … See more There are currently no applications, aside from war, for T-2 mycotoxins; however, there are some plausible therapeutic uses. Due to their abilities, research shows possible uses for … See more This compound has a tetracyclic sesquiterpenoid 12,13-epoxytrichothene ring system, which relates it to the trichothecenes. These compounds are generally very stable … See more The toxicity of T-2 toxin is due to its 12,13-epoxy ring. Epoxides are in general toxic compounds; these react with nucleophiles and then undergo further enzymatic reactions. … See more At the moment, there is no specific therapy for T-2 mycotoxin poisonings. Exposure of the mycotoxin is typically followed by … See more
An update on T2-toxins: metabolism, immunotoxicity
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T 2 Toxin - an overview ScienceDirect Topics
WebJan 29, 2024 · T-2 toxin is type A trichothecenes mycotoxin, which produced by fusarium species in cereal grains. T-2 toxin has been shown to induce a series of toxic effects on the health of human and animal, such as immunosuppression and carcinogenesis. Previous study has proven that T-2 toxin caused hepatotoxic … WebSummary. T-2 toxin (T2) and HT-2 toxin (HT2) belong to the group of compounds known as trichothecenes, which are part of the largest group of Fusarium mycotoxins comprising more than 150 compounds. In 2024, the European Food Safety Authority (EFSA) published a scientific opinion on the appropriateness to set a group health-based guidance value … WebT-2 toxin is another Fusarium produced mycotoxin and is seldom detected in forages of the upper Midwest. T-2 studies document that it causes gastroenteritis in laboratory animals. … podcast hosting free unlimited